Urgently Required Senior Research Associate, Reagent Development – Exai Bio

Senior Research Associate, Reagent Development - Exai Bio - Palo Alto, CA - work from home job

Company: Exai Bio

Job description: What We are Looking For

A highly motivated senior research associate to join the Reagents Development team. As a member of the Reagent Development team, the successful candidate will contribute to the development of robust reagents and QC methods, and support the transfer of our next-generation liquid biopsy platform from design to production in a CLIA lab facility. In this role, the candidate will work closely with the assay development and automation teams to develop effective reagents that perform consistently in the final product, and will be in compliance with any external regulatory requirements. Projects will include complex workflows using a wide variety of tools at the interface of molecular biology, biochemistry and automated liquid handling for nucleic acid extraction, library prep, and NGS as part of our oncRNA technology platform. . You will be a member of a fast-paced cross-functional team with a key focus on coordinating with early research, clinical laboratory operations, computational biology, quality and regulatory teams and develop quality metrics that will efficiently transition the proof-of-concept research assays into a regulated environment.

What You’ll Do
• Design, optimize and validate analytical assays for testing/developing various reagents to maximize the efficiency of automated RNA extraction and sequencing from biofluids
• Develop assay controls and functional QC methods to evaluate assay/reagent performance
• Perform guardbanding/time course experiments to pressure test the assay for reagent stability
• Work with vendors and supply chain to develop reagent/kit formulations and develop purchasing specifications
• Build pilot manufacturing and QC processes
• Maintain clear and detailed experimental records, write SOPs/purchasing specs independently.
• Work with Clinical Laboratory Operations to establish reagent transfer and storage procedures
• Present at lab meetings, contribute to manuscripts for publication in peer reviewed journals.
• Assist in training of new team members

Requirements

What You’ll Bring to the Team
• BS/MS in molecular biology, biochemistry, genomics, or related discipline with a minimum 3-4 years of relevant hands-on experience in complex processes and workflows
• Track record in NGS methods development and/or automating nucleic acid- based workflows. Experience in RNA biology, cell-free nucleic acid biology and/or cancer biology is a plus. Strong preference given to candidates with previous experience of automated assay development.
• Familiarity with functional and component QC methods, data analysis tools such as MATLAB, R, Python is desirable
• Experience with working as part of a multidisciplinary and collaborative team.
• Experience working with vendors and supply chain management for developing purchasing specs is preferred
• Excellent communication and interpersonal skills
• You must be legally authorized to work in the U.S and be fully vaccinated against COVID-19, including all eligible booster(s), with the exception of a medical or religious exemption

Benefits

What You’ll Get as Part of Our Team
• An inspiring working culture where our core values are more than just words on a page. We walk the talk!
• Base Salary Range: Senior Research Associate (BS + 4 years experience or MS + 2 years of experience, $84,000 to $126,000), takes into account factors including experience, skills, location, education and other compensation and benefits being offered. These may include: competitive equity, bonus, 401k matching, paid time off, and other benefits (medical/dental/vision, STD/LTD, Life/AD&D, HSA, FSA).
• Comprehensive Benefits: medical/dental/vision, STD/LTD, Life/AD&D, HSA with employer contribution, FSA, employee assistance program, paid time off, generous holiday schedule, equity and 401k matching.
• Additional Benefits: hybrid and remote work options, commuter benefits, home office subsidy and learning & development opportunities.

What We Value

Our core values represent what we stand for as a team. This is what we believe in. Everyday, we strive to align our behaviors to these core values in everything we do.

Integrity – Our thoughts and actions are true to science and to people. We do the right thing.

Openness – We recognize and respect our differences – and embrace learning from them.

Teamwork – We are team players who trust and respect each other.

Exploration – We are explorers, putting curiosity into action.

Kindness – We are kind whenever possible – and we believe it’s always possible.

More About Us

Exai Bio was founded with technology from the UCSF laboratory of Dr. Hani Goodarzi, and consists of veteran leaders in the RNA biology, liquid biopsy, and artificial intelligence/machine learning fields from both academia (UCSF, Stanford, MIT) and industry (Bluestar, CareDx, Evidation, Google, 23andMe, Deep Genomics). We are backed by leading life sciences and tech investors, including , , and , who have been integral to advancing cancer diagnostics and artificial intelligence/machine learning technologies in past companies like Foundation Medicine, Thrive Earlier Detection, Insitro and Recursion.

We value a diverse, inclusive workforce and we provide equal employment opportunities for all applicants and employees. All qualified applicants will be considered without regard to an individual’s race, color, sex, gender identity, gender expression, religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws.

We do not accept unsolicited resumes from agencies or other third parties and will not pay fees associated with such resumes. Agencies, please do not send resumes to any of our locations, employees or email addresses.
Senior Research Associate, Reagent Development - Exai Bio - Palo Alto, CA - work from home job

Expected salary: $84000 - 126000 per year

Location: Palo Alto, CA
Senior Research Associate, Reagent Development - Exai Bio - Palo Alto, CA - work from home job

Job date: Sun, 22 Jan 2023 05:22:48 GMT

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Senior Research Associate, Reagent Development - Exai Bio - Palo Alto, CA - work from home job

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